The analysis of multimodality ultrasound features of renal cell carcinomas with different tumor sizes

Objectives: To assess multimodality ultrasound features of renal cell carcinomas (RCCs) with different tumor sizes, especially in RCCs ≤ 3 cm in diameter. Patients & Methods: Patients with surgery resection and histopathologically confirmed RCCs were included. All patients underwent multimodality ultrasound examinations one week before surgery. Results: From July 2023 to January 2024, a total of 81 RCCs were finally enrolled, including Group 1 (≤ 3 cm, n = 41) and Group 2 (> 3 cm, n = 40). Hypervascular blood supply could be observed more commonly in RCCs > 3 cm than in RCCs ≤ 3 cm (P = 0.039) by MVI. The median SWV values of RCCs > 3 cm were higher than those in the RCCs ≤ 3 cm (P = 0.038). During arterial phase of CEUS, hyper-enhancement could be observed more often in RCCs > 3 cm (P = 0.246). However, 58.5% (24 / 41) of small RCCs ≤ 3 cm showed relatively late wash out after 60 s (P = 0.005). Conclusions: While comparing to bigger ones, RCCs ≤ 3 cm showed relatively less blood supply in the CDFI and MVI techniques, softer texture, hyperperfusion and later wash out after 60 s on CEUS.