Premenstrual exacerbation of psychiatric symptoms: from misdiagnosis to management

Jayashri Kulkarni1, Eveline Mu1

  • 1HER Centre Australia, Department of Psychiatry, School of Translational Medicine, Monash University, Melbourne, Australia.

Premenstrual exacerbation of existing mental illnesses (PME) is a condition where symptoms of mental disorders worsen during the luteal phase. Unlike premenstrual syndrome or premenstrual dysphoric disorder, PME is poorly recognised, with misdiagnoses and inadequate treatment. Understanding the brain impact of gonadal hormone fluctuations in PME is crucial.

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