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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Neurosteroid treatment of postpartum depression and beyond
Kristina M Deligiannidis1,2,3, Samantha Meltzer-Brody4
1Institute of Behavioral Science, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, USA.
Abstract:
Depression occurring during pregnancy or after delivery is one of the most common complications of childbirth and is associated with maternal morbidity and mortality. Here we review the breakthrough development of the first neuroactive steroid-based antidepressants approved for postpartum depression in the USA and their potential in other psychiatric illnesses.
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