Related Experiment Video
Updated: Jul 19, 2026

11:55
Examining the Conformational Dynamics of Membrane Proteins in situ with Site-directed Fluorescence Labeling
Published on: May 29, 2011
Covalent labeling of the tetrodotoxin receptor in excitable membranes
Abstract:
A photoaffinity labeling technique is described by which a tetrodotoxin analog is covalently bound to receptor sites associated with the sodium pores of excitable membranes. The biological activity of the toxin analog is retained after the covalent binding reaction.
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