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Updated: Jan 18, 2026

Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase
Published on: November 8, 2019
Kinetic studies of the interaction of cannabinoids with singlet oxygen
Carly J Frank1, Neeraj Joshi1, Tony Durst1
1Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada.
Abstract:
The kinetics of the interaction of several cannabinoids with singlet oxygen have been examined in acetonitrile solution using laser flash photolysis techniques and using xanthone as a singlet oxygen sensitizer. Typical rate constants for these Type 2 reactions are in the 1-7 × 107 M-1 s-1 range and are in accordance with typical reactivities for phenolic compounds. Protection of the phenolic function reduces the reactivity by approximately a factor of five, thus confirming that singlet oxygen quenching is dominated by the phenolic group.
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