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Updated: Jan 18, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
Bilateral renal vein thrombosis in a preterm with Netherton syndrome
Ana Roche-Gomez1, Diana Voskanyan2, Joanna Śladowska-Kozłowska3
1Pediatric Nephrology Department, Hospital Universitario 12 de Octubre, Madrid, Spain. ana.rochegomez@gmail.com.
Abstract:
Netherton syndrome (NS) is a rare autosomal recessive syndrome caused by mutations in the serine protease inhibitor of the Kazal type 5 (SPINK5) gene. Patients are characterized by the classic triad of congenital ichthyosiform erythroderma, a hair shaft abnormality termed trichorrhexis invaginata and atopic diathesis. These children require meticulous fluid and salt control from the first day of life to prevent kidney damage due to the defective skin barrier.
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