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Updated: Aug 11, 2026

Engineering Platform and Experimental Protocol for Design and Evaluation of a Neurally-controlled Powered Transfemoral Prosthesis
Published on: July 22, 2014
A clinical decision-making algorithm for the personalized prescription of microprocessor-controlled prosthetic knees:
Carlos Carrasquillo1,2, Sixu Zhou1,2, W Lee Childers3,4
1Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Background:
Current processes for identifying the best microprocessor-controlled prosthetic knee (MPK) for individuals with transfemoral amputations are subjective, nonscientific, and sometimes fail to consider unique patient needs. Inaccurate prescriptions may hinder a patient's ability to make a speedy rehab.
Objectives:
We developed a clinical decision equation that outputs MPK recommendation scores for 3 commercially available MPKs (Power Knee, C-Leg 4.0, Rheo Knee) based on easily acquirable user evaluation data.
Study Design:
Participants wore each of the study MPKs at home for a 1-week acclimation period. On the experiment day, participants completed a set of functional tasks including a 10-m walk test, stair and ramp ambulation tasks, a 2-minute walk test, and a narrow beam walking test. Performance outcome measures were collected.
Methods:
Microprocessor-controlled prosthetic knees were scored relatively to the best performing knee based on their performance in 5 areas of interest: agility, community ambulation, energy, stability, and gait quality. The relative importance of each of these areas was computed based on a quantitative prediction of a user's functional needs from features including age, body mass index (BMI), AMPnoPRO score, and likelihood of stairs/ramps. We describe the algorithm-suggested optimal patient profiles for each device.
Results:
We developed an application that allows clinicians to obtain instant recommendations. Clinicians can further adjust the relative importance of each area of interest based on patient needs.
Conclusions:
This algorithm represents a transparent, experimentally backed clinical decision-making aid with the potential to streamline the prosthesis fitting process. Future studies are required to evaluate the effectiveness of the algorithm.