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Multidisciplinary approach and combination pharmacotherapy for the management of cardiometabolic patients

Giuseppe M C Rosano1,2, Cristiana Vitale3, Ilaria Spoletini4

  • 1Department of Human Sciences and Promotion of Quality of Life, San Raffaele Open University of Rome, Rome, Italy.

Journal of Cardiovascular Medicine (Hagerstown, Md.)
|June 5, 2025
PubMed

Insights

Cardiometabolic disorders frequently co-occur, necessitating a multidisciplinary approach for effective patient management. Targeting common pathways like inflammation and oxidative stress is crucial for treating these interconnected conditions.

Area of Science:

  • Cardiology
  • Endocrinology
  • Primary Care

Background:

  • Cardiometabolic disorders such as hypertension, coronary artery disease, dyslipidaemia, heart failure, and diabetes often cluster in patients.
  • This clustering indicates shared pathogenic mechanisms, including inflammation and oxidative stress.

Purpose of the Study:

  • To emphasize the need for a multidisciplinary approach in managing patients with co-occurring cardiometabolic disorders.
  • To highlight the importance of targeting common pathogenic mechanisms in treatment strategies.

Main Methods:

  • A consensus document was developed based on discussions from a forum involving experts in cardiology, endocrinology, and primary care.
  • Key highlights from the forum discussions were synthesized.

Main Results:

  • Cardiometabolic disorders often present as a cluster of related conditions in patients.
  • Therapeutic interventions targeting common pathogenic mechanisms are expected to impact multiple disorders simultaneously.
  • A combined treatment approach is superior to siloed specialty care.

Conclusions:

  • A multidisciplinary approach is essential for managing patients with complex cardiometabolic conditions.
  • Interventions addressing shared pathways like inflammation and oxidative stress are vital for comprehensive cardiometabolic care.

Keywords:
cardiometabolic disorderscoronary artery diseasediabetesdyslipidaemiaheart failurehypertensionmultidisciplinary approach

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