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A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
Impact of COVID-19 on clinical characteristics in type 2 diabetes patients: A prospective, longitudinal,
Tabinda Azim1, Amer Hayat Khan2, Fouzia Sadiq3
1School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.; Iqra University Islamabad Campus, H-9,Islamabad 44000, Pakistan.
Aims:
This prospective longitudinal study aimed to evaluate the impact of COVID-19 on glycemic control and hematological parameters in patients with pre-existing type 2 diabetes.
Methods:
Data for this study was collected from outpatient Endocrinology Departments of tertiary and secondary care hospitals in Islamabad, Pakistan, between November 2022 and April 2024. Out of the 604 patients initially enrolled, only 420 completed the nine-month study with full clinical data across three follow-up visits and were included in the final analysis.
Results:
At baseline, COVID-19-positive type 2 diabetes patients (case group) exhibited significantly higher HbA1c, and random blood glucose levels with lower white blood cell, red blood cell, hemoglobin, and platelet counts (p < 0.001) as compared to the control group. On the last follow-up visit, the random blood glucose indicated statistically higher levels (180.5 ± 51.4) in the case group, as compared to the control (160.8 ± 51.5)(p = 0.035). Improvement in haematological parameters was observed in both groups on the last follow-up visit.
Conclusions:
This study demonstrates a significant association between COVID-19, poor glycemic control, and clinical characteristics in type 2 diabetes patients over an extended period, highlighting the need for ongoing monitoring and management in this vulnerable population.
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