A novel 16-hydroxy-palmitic acid tethered D-configured homo-chiral triphenylalanine based nanofibrillar scaffold with innate anticancer potential
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Vaibhav Shivhare1, Arindam Gupta2, Rishabh Ahuja1
1Department of Chemistry, Rajiv Gandhi Technological University, Bhopal, India. anitaduttkonar@rgpv.ac.in.
Chemical Communications (Cambridge, England)
|June 6, 2025
Abstract:
A homochiral triphenylalanine system when tethered to 16-hydroxy-palmitic acid at the N-terminus displays excellent gelation propensity with mechanoresponsiveness and innate anticancer potential. We anticipate that the amphiphile-lactate derivative compound VI plays a pivotal role in addressing the cancer related challenges probably via an extrinsic apoptotic pathway.
