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Genomic Full-Length Sequence of the HLA-DRB1*04:90 Allele Was Identified by PacBio Sequencing

Bin Hu1, Qi Yu1, Li Liu1

  • 1HLA Typing Laboratory, Institute of Transfusion Medicine, Qingdao Blood Center, Qingdao, Shandong Province, China.

HLA
|June 6, 2025
PubMed

Abstract:

The complete genomic sequence of HLA-DRB1*04:90 was determined using a PacBio sequencing approach conducted in China.

Keywords:
HLA‐DRB1*04:90PacBio sequencinggenomic full‐length

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...

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