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Updated: Sep 19, 2025

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Management of enterocutaneous (jejunocutaneous) fistulas with NBCA glue injection: A case report
Paria Bolourinejad1, Ghazal Zandieh2, Pardis Tavallaeinejad2
1Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Abstract:
This case report highlights a minimally invasive approach to the management of enterocutaneous fistulas (ECFs), specifically jejunocutaneous fistulas (JCFs), using n-butyl cyanoacrylate (NBCA) glue. The patient, a 77-year-old female with Crohn's disease, presented with abdominal pain, fever, chills, and persistent discharge from the JCF site. Conventional treatment options for ECFs, ranging from conservative management to surgical intervention, are often associated with morbidity and prolonged recovery periods. This case demonstrates the successful closure of a JCF using NBCA glue injection, resulting in complete symptom resolution and sustained fistula closure at 18 months follow-up. The application of NBCA glue represents a promising alternative to traditional approaches, offering reduced procedural risks and shorter recovery times. This report highlights the role of minimally invasive techniques in the management of ECFs and highlights the need for further studies to establish standardized protocols and expand the clinical use of this approach.
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