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Giant malignant phyllodes tumor: A case report.

Daniela Kerguelen Murcia1, Andrea Tenreiro2, Jennifer A Kohlnhofer2

  • 1John Sealy School of Medicine, University of Texas Medical Branch, Galveston, TX, USA.

Radiology Case Reports
|June 6, 2025
PubMed
Summary
This summary is machine-generated.

Phyllodes tumors are rare, fast-growing breast masses. This case highlights a giant malignant phyllodes tumor, emphasizing the need for accurate diagnosis and management of this uncommon condition.

Keywords:
Breast imagingBreast massPhyllodes tumorRadiology

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Area of Science:

  • Oncology
  • Pathology
  • Radiology

Background:

  • Phyllodes tumors are rare fibroepithelial breast neoplasms.
  • They are distinguished from fibroadenomas by their rapid growth rate.

Observation:

  • This report details a giant malignant phyllodes tumor in a 53-year-old female.
  • The tumor presented as a rapidly enlarging, multinodular breast mass.

Findings:

  • Ultrasound revealed a hypoechoic solid mass with cystic components.
  • Mammography showed a hyperdense lesion.
  • Histological examination confirmed leaf-like architecture and high stromal cellularity, indicative of malignancy.

Implications:

  • Early and accurate diagnosis of phyllodes tumors is crucial.
  • Malignant phyllodes tumors require prompt surgical management, such as mastectomy.
  • Understanding radiologic and histologic features aids in differentiating phyllodes tumors from benign breast lesions.