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Updated: Sep 19, 2025

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
Published on: January 10, 2019
cellSight: Characterizing dynamics of cells using single-cell RNA-sequencing
Ranojoy Chatterjee1, Chiraag Gohel1, Brett A Shook2
1Computational Biology Institute, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, The George Washington University, Washington, DC 20052.
Abstract:
Single-cell analysis has transformed our understanding of cellular diversity, offering insights into complex biological systems. Yet, manual data processing in single-cell studies poses challenges, including inefficiency, human error, and limited scalability. To address these issues, we propose the automated workflow cellSight, which integrates high-throughput sequencing in a user-friendly platform. By automating tasks like cell type clustering, feature extraction, and data normalization, cellSight reduces researcher workload, promoting focus on data interpretation and hypothesis generation. Its standardized analysis pipelines and quality control metrics enhance reproducibility, enabling collaboration across studies. Moreover, cellSight's adaptability supports integration with emerging technologies, keeping pace with advancements in single-cell genomics. cellSight accelerates discoveries in single-cell biology, driving impactful insights and clinical translation. It is available with documentation and tutorials at https://github.com/omicsEye/cellSight.
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