Human milk-derived growth factor prevents duodenal ulcer formation

Human milk was fractionated to obtain a partially purified growth factor preparation. The growth factor in this fraction, designated as human milk growth factor III, exhibits chromatographic and biological characteristics similar to epidermal growth factor-urogastrone. Pretreatment of mice with human milk growth factor III significantly reduces the incidence, number, total length, and severity score of cysteamine-induced duodenal ulcers.