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Evidence and Consensus-Based Imaging Guidelines in Serpiginous Choroiditis-Multimodal Imaging in Uveitis (MUV) Task
Aniruddha Agarwal1, Anita Agarwal2, Debra A Goldstein3
1From the The Eye Institute (Aniruddha A.), Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; Cleveland Clinic Lerner College of Medicine (Aniruddha A.), Cleveland, Ohio, USA.
American Journal of Ophthalmology
|June 6, 2025
Summary
This study establishes imaging guidelines for serpiginous choroiditis (SC) using multimodal imaging. These consensus-based recommendations aid in diagnosing SC, assessing disease activity, and managing complications.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Serpiginous choroiditis (SC) is a rare inflammatory eye condition.
- Accurate diagnosis and monitoring of SC are crucial for effective management.
Purpose of the Study:
- To develop consensus-based guidelines for multimodal imaging in serpiginous choroiditis (SC).
- To standardize the application of imaging techniques for SC diagnosis and assessment.
Main Methods:
- A literature search and expert committee using a nominal group technique were employed.
- Informatics-driven criteria selected high-quality imaging cases (CFP, OCT, FFA, ICG, OCTA).
- Consensus was reached on imaging use for disease characteristics, activity biomarkers, and complications.
Main Results:
- Color fundus photography (CFP) and fundus autofluorescence are key for SC diagnosis.
- Fundus autofluorescence is vital for assessing disease activity.
- FFA, OCT, and OCT angiography (OCTA) help identify choroidal neovascularization and differentiate SC from other conditions.
Conclusions:
- The developed imaging criteria extend the Standardization of Uveitis Nomenclature (SUN) classification.
- These guidelines provide a framework for evaluating SC activity and complications.
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