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Updated: Sep 19, 2025
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Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
Published on: December 9, 2015
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Novel knockdown resistance mutations in human lice: artifacts or emerging resistance?
Om P Singh1, Rajnikant Dixit1, David Weetman2
1ICMR-National Institute of Malaria Research, Sector 8, Dwarka, New Delhi-110077, India.
Trends in Parasitology
|June 6, 2025
Abstract
None:
An exceptionally high number of novel mutations within domain II of the voltage-gated sodium channel have been reported in human lice from Iran and Saudi Arabia. We critically evaluate these reports, highlighting that many of them may be methodological artifacts, and urge rigorous confirmation before assigning biological significance.
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