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Contrast Ultrasound Targeted Treatment of Gliomas in Mice via Drug-Bearing Nanoparticle Delivery and Microvascular Ablation
Published on: December 15, 2010
"Target Sign" of Schwannoma on Contrast-Enhanced Ultrasound
1Department of Ultrasound, Peking University Third Hospital, Beijing, China.
None:
This case series investigates the "Target sign" in contrast-enhanced ultrasound (CEUS) of 11 pathologically confirmed schwannomas, characterized by early central hyperenhancement (mean TTP: 15.7 ± 3.2 s) surpassing peripheral regions (19.1 ± 2.8 s). CEUS demonstrated 100% detection of this sign, outperforming grayscale ultrasound (45%), correlating with histologic Antoni A (cellular) and B (myxoid) areas. Findings suggest CEUS improves diagnostic specificity for schwannomas, offering non-invasive microvascular mapping. Limitations include small sample size and retrospective design.
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