Related Experiment Video

Updated: Jan 18, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
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Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

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Clostridioides difficile evolution in a tertiary German hospital through a retrospective genomic characterization

Fabian Lorenzo-Diaz1,2, Tilman E Klassert3,4, Cristina Zubiria-Barrera3,4

  • 1Genomics and Health Group, Departamento de Bioquímica, Microbiología, Biología Celular y Genética, Facultad de Ciencias, Canary Islands, Universidad de La Laguna, La Laguna, Spain. florenzo@ull.edu.es.

Infection
|June 8, 2025
PubMed
Summary

Clostridioides difficile strains evolved over two decades, with ST1 becoming dominant. Antimicrobial resistance patterns shifted, highlighting the need for integrated genetic surveillance and antibiotic stewardship to manage healthcare-associated infections.

Keywords:
Antibiotic resistance genesCDIClostridioides difficilePaLocWGS

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