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[Morbidity and mortality indicators of diabetic peripheral artery vascular patients in a general practice]
Henrietta Galvács1,2, Istvánné Mongel2, Katalin Dózsa2,3
11 Semmelweis Egyetem, Egészségtudományi Kar Budapest, Vas u. 17., 1088 Magyarország.
Insights
Diabetic patients have a significantly higher risk of developing lower extremity peripheral artery disease, especially those with longer diabetes duration and other cardiovascular risk factors. Early screening and integrated care are crucial for prevention.
Area of Science:
- Cardiology
- Endocrinology
- Public Health
Background:
- Diabetes mellitus is a major public health concern with significant cardiovascular complications.
- Lower extremity peripheral artery disease (PAD) is a critical complication of diabetes.
- Early identification and management of PAD risk factors in diabetic patients are essential.
Purpose of the Study:
- To determine the prevalence and risk factors of lower limb PAD in patients with carbohydrate metabolism disorders.
- To compare PAD risk in diabetic versus non-diabetic patients within a primary care setting.
- To inform preventive strategies in general practice.
Main Methods:
- Prospective evaluation of 423 patients over three years (2021-2024).
- Data collection included anthropometric measurements, comorbidities, and ankle-brachial index (ABI).
- Comparison of PAD prevalence and risk factors between diabetic and non-diabetic patient groups.
Main Results:
- Diabetic patients exhibited significantly higher waist circumference and BMI.
- PAD risk was significantly influenced by male gender, smoking, diabetes duration, fasting glucose, and comorbidities like coronary artery disease, kidney disease, dyslipidemia, and carotid stenosis.
- Increased PAD risk was observed in diabetic patients from age 45, with a high mortality risk by age 70.
Conclusions:
- Diabetic patients frequently present with PAD and other cardiovascular conditions, often indicating polyvascular disease.
- A holistic primary care approach, including cholesterol management, is vital.
- Integrating advanced practice nurses into primary care can enhance chronic disease screening, patient education, and management, improving preventive care outcomes.
Abstract:
Introduction: Diabetes mellitus is one of the most serious public health problems today. Among its target organ complications, cardiovascular diseases stand out. Among these, one of the most significant diseases is lower extremity peripheral artery disease. Objective: The aim of this study was to assess the prevalence, risk factors and risk of lower limb peripheral artery disease in patients with carbohydrate metabolism disorder attending a preventive care office in a general practice, compared with non-diabetic patients. Method: Between 01. 06. 2021 and 31. 05. 2024, we evaluated the anthropometric data, comorbidities, and ankle-brachial index results of patients who attended the preventive care office, using the general practice software, comparing diabetic and non-diabetic patients. Results: During the examined period, 522 care events took place, involving 423 patients. A significant difference was found between the waist circumference (p<0.001) and BMI values (p<0.001) of diabetic and non-diabetic patients. Cardiovascular diseases also occurred significantly more frequently (p<0.001) in diabetes. In addition to male gender (p = 0.041), smoking (p = 0.034), diabetes duration (p = 0.018), fasting blood glucose level (p = 0.039), chronic coronary artery disease (p<0.001), chronic kidney disease (p = 0.041), dyslipidemia (p = 0.021), and pre-existing carotid plaque/stenosis (p = 0.002) showed significant influencing effects on the development of peripheral artery disease. The risk of developing peripheral artery disease is already increased in diabetic patients from the age of 45 years, and by the age of 70 years, the majority of patients may be dead. Discussion: Lower extremity peripheral artery disease and other known cardiovascular conditions occurred significantly more frequently in diabetic patients. Most of them can be considered polyvascular patients due to the involvement of other localizations (carotid system and coronary arteries). Due to the confirmed comorbidities, a holistic approach is necessary in primary care, an important part of which is achieving cholesterol target levels. Conclusion: In order for prevention to be more successful, it is necessary to involve additional professionals in the primary care of diabetic patients as soon as possible, in the spirit of task delegation. In the screening of chronic diseases, patient education, and care to the target value, advanced practice nurses can provide effective assistance, making their prompt integration fundamentally important. Orv Hetil. 2025; 166(23): 913–920.
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