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Updated: Jun 13, 2025

Identification and Dissection of Diverse Mouse Adipose Depots
Published on: July 11, 2019
Adipose tissue and androgens: the ins and outs
Yiyue Jia1, Mathilde Lacombe1, Catherine Muller1
1Équipe Labellisée Ligue Nationale contre le Cancer, Institut de Pharmacologie et de Biologie Structurale, CNRS/Université de Toulouse UMR, Toulouse, France.
None:
Adipose tissue (AT), one of the largest endocrine tissues in the human body, is an important site for the storage and production of steroid hormones. In particular, AT's capacity to produce androgens could enable it to have a regulatory role in local or general hormone homoeostasis. The links between obesity, polycystic ovary syndrome (PCOS), metabolic disorders, and hormonal balance emphasise the importance of understanding the intricate relationships between AT and androgen dynamics within AT. This review, focusing on androgen metabolism, summarises the androgen profile in white adipose tissue (WAT) and brown adipose tissue (BAT) of humans and animal models, along with the androgen-metabolising enzymes present in WAT, and explores the role of androgens on AT physiology.
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