Electrocardiographic markers in Motoric Cognitive Risk syndrome

Area of Science:

• Cardiology
• Neurology
• Geriatrics

Background:

• Motoric Cognitive Risk (MCR) syndrome, a pre-dementia condition, is associated with cardiovascular disease.
• Electrocardiograms (ECGs) offer a non-invasive method to detect cardiac abnormalities.

Purpose of the Study:

• To investigate the association between ECG abnormalities and prevalent MCR in older adults.
• To assess the utility of ECGs for cardiovascular disease risk stratification in MCR.

Main Methods:

• Analysis of ECGs from 451 older adults in the Kerala Einstein Study (KES).
• Logistic regression adjusted for age and sex to determine odds ratios (OR) and 95% confidence intervals (CI).

Main Results:

• ECG abnormalities were found in 42.4% of participants.
• MCR patients showed higher prevalence of abnormal Q waves (OR 5.1) and heart block (OR 6.0).
• No significant differences in other ECG abnormalities were observed between MCR and control groups.

Conclusions:

• ECG abnormalities are frequent in individuals with MCR syndrome.
• ECGs can be a valuable tool for cardiovascular disease risk stratification in MCR cases.