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Related Experiment Video

Updated: Jun 12, 2025

Stereotactic Radiosurgery for Gynecologic Cancer
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Prostate Stereotactic Body Radiotherapy With Synchrony®-Based Fiducial Tracking on Radixact® X9.

Adithya Vikrama Acharya1, Sanjay Hunugundmath2, Mariya Deputy1

  • 1Radiation Oncology, Sahyadri Superspeciality Hospital, Pune, IND.

Cureus
|June 9, 2025
PubMed
Summary
This summary is machine-generated.

Stereotactic body radiation therapy (SBRT) offers an effective treatment for localized prostate cancer. This study details clinical experience using advanced tomotherapy with real-time motion tracking for precise SBRT delivery.

Keywords:
extreme hypofractionationfiducial-based trackinghelical tomotherapyimage-guided radiotherapylate-reacting tissuelocalized prostate cancerprostate hypofractionationreal-time intrafraction managementreduced treatment timestereotactic ablative body radiotherapy (sbrt)

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Area of Science:

  • Oncology
  • Radiation Oncology
  • Medical Physics

Background:

  • Early-stage prostate cancer management includes active observation or radical treatment.
  • Radical options include surgery, external beam radiotherapy (EBRT), and brachytherapy.
  • EBRT encompasses conventionally fractionated (CF-RT) and hypofractionated techniques, including stereotactic body radiation therapy (SBRT).

Purpose of the Study:

  • To report clinical experience with prostate SBRT.
  • To evaluate the use of a specific tomotherapy system with real-time motion tracking for SBRT.

Main Methods:

  • Case series reporting clinical experience with prostate SBRT.
  • Utilized the Radixact® X9 tomotherapy machine (Accuray).
  • Employed Synchrony® fiducial tracking for real-time intrafraction motion management.

Main Results:

  • SBRT is demonstrated as non-inferior to CF-RT in recent studies.
  • National Comprehensive Cancer Network guidelines support SBRT for localized prostate cancer.
  • SBRT requires precise targeting and motion management due to high dose per fraction.

Conclusions:

  • Prostate SBRT is a viable treatment option for localized disease.
  • Advanced technology enables precise SBRT delivery with motion correction.
  • This approach aims to minimize toxicity by protecting organs at risk.