Related Experiment Video
Updated: Jun 12, 2025

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound 30/45MHZ System
Published on: May 5, 2018
On-Table Hypoxic Arrest: A Comparative Examination of Peripartum Cardiomyopathy and Pre-eclampsia
Clara Tong1, Aaron Kong2, Farida Ithnin2
1Department of Anaesthesiology and Surgical Intensive Care, Changi General Hospital, Singapore, SGP.
Insights
This case study highlights successful management of severe pulmonary edema in a pre-eclamptic patient. Early diagnosis and intervention, including a peri-mortem Cesarean, were crucial for a positive outcome in this high-risk pregnancy.
Area of Science:
- Obstetrics and Gynecology
- Cardiology
- Critical Care Medicine
Background:
- Pre-eclampsia (PE) and peripartum cardiomyopathy (PPCM) are serious pregnancy complications.
- Pulmonary edema can present similarly in both conditions, complicating diagnosis and management.
- Severe maternal morbidity requires prompt and expert intervention.
Abstract:
Pre-eclampsia (PE) and peripartum cardiomyopathy (PPCM) are two types of complications that can occur in pregnancy and the peripartum period. We present the successful management of a pre-eclamptic patient with severe, undifferentiated pulmonary oedema in pregnancy. Our patient presented at 35 + 5 weeks of gestational age with hypertension, delirium and severe hypoxaemia. She developed pulseless electrical activity after induction of general anaesthesia for a category one caesarean section. Resuscitation commenced, and a peri-mortem caesarean section was performed. Spontaneous circulation returned nine minutes after arrest. Post-operative evaluation in the intensive care unit revealed elevated natriuretic peptide levels, cardiomegaly and left ventricular ejection fraction of 20%-25%. Pulmonary oedema associated with PE and PPCM may have similar clinical features but may be distinguished with a targeted bedside echocardiogram. This guides disease-specific management and prognostication. Strategies to prevent severe hypoxaemia during laryngoscopy and intubation may also be considered. These cases require expert care and good inter-disciplinary team dynamics to ensure a favourable patient outcome.

