Massive Solitary Fibrous Tumor of the Hypopharynx

We present the case of a 38-year-old female patient diagnosed with a solitary fibrous tumor (SFT) of the right hypopharynx, a rare and atypical localization of this mesenchymal neoplasm. SFT is a rare entity. Most SFTs are benign tumors commonly arising in the pleura, while extrapleural occurrence in locations such as the head and neck region is also well recognized. The aim of this report is to describe this rare clinical presentation, discuss the diagnostic complexities it entails, and emphasize the critical role of complete surgical excision as the mainstay of treatment, as radiation or chemotherapy protocols are not well established or have been proven to be ineffective. Recurrence is mostly associated with incomplete resection, and malignant transformations have been described. Given the challenging anatomic location of the tumor in our patient, a total laryngectomy was required to achieve complete tumor removal.