Correlation Between Ultrasonographic Features and Histopathological Findings in Breast Lesions

Area of Science:

• Radiology
• Oncology
• Pathology

Background:

• High-resolution ultrasound is a valuable tool for breast lesion characterization.
• Accurate differentiation between benign and malignant breast masses is crucial for patient management.

Purpose of the Study:

• To evaluate the correlation between specific ultrasound findings and histopathological diagnoses of breast lesions.
• To determine the diagnostic utility of ultrasound features in distinguishing benign from malignant breast masses.

Main Methods:

• Retrospective analysis of ultrasound images and histopathology reports from 153 ultrasound-guided breast biopsies.
• Lesions were assessed using the Breast Imaging Reporting and Data System (BI-RADS) Ultrasound Lexicon for features including shape, margin, echotexture, and calcification.
• Correlation of ultrasound characteristics with histological outcomes.

Main Results:

• Of 153 lesions, 119 (77.78%) were benign and 34 (22.22%) were malignant.
• Fibroadenoma was the most common benign lesion (55 cases), while invasive carcinoma of no specific type was the most common malignant lesion (25 cases).
• Age, shape, orientation, margins, and calcification showed significant association with lesion malignancy.

Conclusions:

• Ultrasound features such as shape, margin, calcification, and orientation are significant predictors of breast lesion nature.
• These ultrasound characteristics, combined with patient age, assist in differentiating benign from malignant breast masses.
• High-resolution ultrasound plays a vital role in the preoperative assessment of breast lesions.