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Contemporary Perspectives on Chronic Renal Disorders.
Deenadhayalan Ashok1, Poornima Ajay Manjrekar1, Bhushan C Shetty2
1Department of Biochemistry, Kasturba Medical College Mangalore Manipal Academy of Higher Education Manipal Karnataka India.
Chronic Diseases and Translational Medicine
|June 9, 2025
Summary
Advancements in renal research focus on cellular and molecular understanding of kidney diseases. Novel biomarkers and omics technologies are improving diagnostics and personalized medicine for better patient outcomes.
Area of Science:
- Nephrology
- Biomarker Discovery
- Personalized Medicine
Background:
- Increasing prevalence and healthcare burden of renal diseases.
- Shift from basic markers to cellular/molecular understanding.
- Focus on quality of life, disease progression, and personalized treatments.
Purpose of the Study:
- Highlight improvements in kidney disease diagnostic applications.
- Discuss notable biomarkers and high-throughput omics technologies.
- Present contemporary perspectives on renal research.
Main Methods:
- Comprehensive literature search across major databases (PubMed, Scopus, Web of Science, Medline).
- Inclusion of relevant Mesh terms for search strategy.
- Documentation of relevant evidence.
Main Results:
- Omics strategies, language models, and pharmacognosy enhance understanding of renal disease.
- Discovery of noninvasive biomarkers, including urine peptide classifiers for fibrosis.
- Biomarker research improves specificity and sensitivity for diagnosis.
Conclusions:
- Renal research is a dynamic field driving advancements in personalized medicine and patient-centered outcomes.
- Developments offer promise for individuals affected by kidney diseases.
- Understanding disease etiology is key for future research and therapeutic interventions.
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