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Dall-E in hand surgery: Exploring the utility of ChatGPT image generation
Daniel Soroudi1, Daniel S Rouhani1, Alap Patel2
1University of California San Francisco, School of Medicine, San Francisco, CA, USA.
Surgery Open Science
|June 9, 2025
Summary
Artificial intelligence (AI) tools like ChatGPT-4.5 and GPT-4o show promise for hand surgery education, offering accurate text and visuals. However, further refinement is needed before widespread clinical adoption of these AI technologies.
Area of Science:
- Medical Education
- Artificial Intelligence in Surgery
- Hand Surgery
Background:
- Artificial intelligence (AI) is increasingly impacting medical fields, including plastic and hand surgery.
- Large language models (LLMs) like ChatGPT and text-to-image generators (e.g., DALL-E, GPT-4o) are becoming more prevalent.
- This study investigates the utility of these AI tools for patient and medical education in hand surgery.
Purpose of the Study:
- To evaluate the capabilities and limitations of AI chatbots (ChatGPT-4.5, ChatGPT-3.5) and text-to-image generators (GPT-4o, DALL-E 3, DALL-E 2) in hand surgery education.
- To assess the accuracy, understandability, and actionability of AI-generated content.
- To compare the performance of different AI models in generating educational materials.
Main Methods:
- Utilized Google Trends data to identify common hand surgery search terms across five categories.
- Queried ChatGPT-4.5 and ChatGPT-3.5 with identified terms and evaluated responses using DISCERN, PEMAT, and Flesch-Kincaid Grade Level.
- Assessed visual representations generated by GPT-4o, DALL-E 3, and DALL-E 2 based on selected ChatGPT responses.
Main Results:
- ChatGPT-4.5 demonstrated superior performance over ChatGPT-3.5 across all metrics, achieving a DISCERN score of 3.80, PEMAT understandability of 91.67%, and accuracy of 4.47.
- AI-generated text had an average Flesch-Kincaid Grade Level of 9.26, indicating a high school reading level.
- GPT-4o generated more accurate visuals compared to DALL-E 3 and DALL-E 2.
Conclusions:
- ChatGPT-4.5 and GPT-4o show potential for enhancing hand surgery education through combined text and image generation.
- Current AI tools possess strengths and weaknesses that require further development for reliable clinical application.
- Additional refinement of AI technologies is necessary prior to their widespread integration into surgical education and practice.

