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Updated: Jan 18, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
Digital Inclusion in Parkinson's Disease: A Case-Control Study
Vincenzo Canoro1, Andrea Pilotto2, Francesco Lena3
1Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", Neuroscience Section University of Salerno, Baronissi, Italy.
People with Parkinson's disease (pwPD) experience significant digital exclusion, particularly in digital skills, hindering telemedicine access. This exclusion worsens with disease severity, impacting those most in need of remote care.
Area of Science:
- Neurology
- Digital Health
- Gerontology
Background:
- Parkinson's disease (pwPD) patients are ideal candidates for telemedicine.
- Digital exclusion poses a significant barrier to implementing telemedicine for pwPD.
Purpose of the Study:
- To compare digital inclusion levels between pwPD and healthy controls (HC).
- To identify socio-demographic and disease-specific factors influencing digital exclusion in pwPD.
Main Methods:
- 490 pwPD and 140 HC completed the Digital Inclusion Questionnaire (DIQUEST).
- Data collected included demographics and clinical characteristics (Hoehn & Yahr, MDS-UPDRSIII, depression, cognitive decline).
- Nonparametric tests and multivariate linear regression analyzed digital exclusion predictors.
Main Results:
- pwPD exhibited greater digital exclusion than HC, primarily due to lower digital skills.
- Depression, apathy, and mild cognitive decline correlated with increased digital exclusion.
- Parkinson's disease presence and severity independently predicted higher digital exclusion.
Conclusions:
- pwPD face substantial digital exclusion, limiting telemedicine adoption.
- Individuals with more advanced Parkinson's disease are paradoxically more digitally excluded, despite greater need for remote services.
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