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Persistent Palmar Rash Associated with Teprotumumab Treatment
Lance R He1, George A Villatoro, Michael T Yen
1Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, U.S.A.
A persistent bilateral palmar rash developed in a patient during and after teprotumumab treatment for thyroid eye disease. This previously unreported side effect underscores the need for vigilant monitoring of adverse events associated with this therapy.
Area of Science:
- Ophthalmology
- Endocrinology
- Dermatology
Background:
- Thyroid eye disease (TED) is an autoimmune condition affecting the eye socket.
- Teprotumumab is an insulin-like growth factor 1 receptor (IGF-1R) inhibitor used to treat TED.
- Adverse events associated with teprotumumab are being increasingly documented.
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