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Treatment and survival of patients with heart failure: An updated analysis from the Czech National Healthcare

Josef Danek1, Jiri Jarkovsky2, Klara Benesova2

  • 1Department of Medicine, First Faculty of Medicine, Charles University and Military University Hospital Prague, U Vojenske nemocnice 1200, 169 02, Prague 6, Czech Republic.

Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
|June 9, 2025
PubMed

Insights

Heart failure (HF) prevalence is rising in the Czech Republic, impacting healthcare. While hospitalizations slightly decreased, enhanced outpatient care and guideline-directed medical therapy (GDMT) are crucial for better patient outcomes.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Heart failure (HF) presents a significant global health challenge with increasing prevalence.
  • This study analyzes HF trends in the Czech Republic from 2015 to 2023.

Purpose of the Study:

  • To provide an updated analysis of heart failure incidence, prevalence, hospitalizations, and mortality.
  • To examine trends in HF management and pharmacotherapy use.

Main Methods:

  • Retrospective observational study utilizing the Czech National Healthcare Reimbursement Database (NRHZS).
  • Inclusion of patients diagnosed with heart failure (ICD-10 codes I50.x).
  • Descriptive statistics and trend analyses were employed.

Main Results:

  • HF prevalence increased significantly, reaching 374,837 patients in 2023, with the highest rates in the 75-79 age group.
  • HF incidence remained stable, while hospitalizations saw a slight decline.
  • In-hospital mortality stabilized around 10%, with increased use of SGLT2 inhibitors and ARNIs.

Conclusions:

  • The healthcare burden of heart failure remains substantial despite treatment advancements.
  • Improving outpatient care and adherence to guideline-directed medical therapy (GDMT) are key to reducing hospitalizations and enhancing patient outcomes.
Abstract

Keywords:
Czech Republicepidemiologyheart failurehospitalizationmortalitypharmacotherapy

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