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Updated: Jan 18, 2026
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Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
Published on: April 11, 2025
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Higher-Order Visuospatial Processing Abilities in Cerebral Visual Impairment: Behavioral Assessment and
Lotfi B Merabet1, Claire E Manley1, Zahide Pamir2,3
1The Laboratory for Visual Neuroplasticity, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA;
Annual Review of Vision Science
|June 9, 2025
Summary
Cerebral visual impairment (CVI) involves brain-based visual processing issues. This review highlights visuospatial deficits and impaired motion processing as core CVI features, impacting interaction with the visual world.
Area of Science:
- Neuroscience
- Ophthalmology
- Developmental Psychology
Background:
- Cerebral visual impairment (CVI) is a brain-based visual disorder.
- It stems from early injury or maldevelopment of visual pathways.
- CVI presents a broad and complex clinical profile of visual dysfunctions.
Purpose of the Study:
- To review visuospatial processing deficits as a core feature of CVI.
- To focus on evidence from behavioral and neuroimaging studies.
- To explore neurophysiological mechanisms underlying CVI visual impairments.
Main Methods:
- Review of behavioral studies on complex motion processing and visual search.
- Analysis of functional and structural neuroimaging findings.
- Synthesis of evidence on higher-order visual processing in CVI.
Main Results:
- Visuospatial processing deficits are a central characteristic of CVI.
- Impaired complex motion processing and visual search abilities are evident.
- Neuroimaging reveals insights into the neurophysiological basis of CVI.
Conclusions:
- Higher-order visual processing dysfunction in CVI arises from impaired bottom-up and top-down processing.
- This imbalance leads to challenges in interpreting and interacting with the visual environment.
- Understanding these mechanisms is crucial for addressing CVI.
Keywords:
cerebral visual impairmentfunctional visionmotion processingneuroimagingvisual searchvisuospatial processingMore Related Videos
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