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Updated: Jan 18, 2026

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Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
Published on: February 12, 2015
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Evaluating the Safety of Rhinoplasty in Smokers
Buğra Tugertimur1,2, Shaishav Datta3, Paige Goote2
1From the New York Plastic Surgical Group.
Plastic and Reconstructive Surgery
|June 9, 2025
Summary
This study found that active smoking is not a strict contraindication for rhinoplasty. Smokers and nonsmokers had similar rates of revision, infection, and wound complications after the procedure.
Area of Science:
- Plastic Surgery
- Otolaryngology
- Wound Healing Research
Background:
- Smoking negatively impacts tissue perfusion and wound healing, crucial factors in rhinoplasty outcomes.
- While the nose has a rich blood supply, postoperative complications in smokers remain a concern.
- This study evaluates if smoking necessitates a contraindication for rhinoplasty, comparing outcomes between smokers and nonsmokers.
Purpose of the Study:
- To determine if active smoking is a contraindication for rhinoplasty.
- To compare infection and revision rates in smokers versus nonsmokers undergoing rhinoplasty.
- To assess the safety and efficacy of rhinoplasty in smokers with proper perioperative management.
Main Methods:
- Retrospective review of 1884 open rhinoplasty cases (2014-2022) with over 12 months follow-up.
- Patients classified as active smokers, former smokers, or nonsmokers.
- Analysis of infection and revision rates, with statistical comparisons between groups.
Main Results:
- No significant differences in revision rates (3.8% smokers vs. 3.3% nonsmokers) or postoperative infections were observed.
- Smokers had a slightly higher rate of cellulitis requiring antibiotics (3.8% vs. 1.6%), resolving without long-term issues.
- Overall, complication rates were comparable between smokers and nonsmokers, indicating similar safety profiles.
Conclusions:
- Active smoking is not an absolute contraindication for rhinoplasty.
- Rhinoplasty outcomes are similar for smokers and nonsmokers when appropriate perioperative care is provided.
- Smoking cessation is advisable but may not be mandatory for successful rhinoplasty results.
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