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Updated: Jan 18, 2026

Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
Published on: February 12, 2015
Evaluating the Safety of Rhinoplasty in Smokers
Buğra Tugertimur1,2, Shaishav Datta3, Paige Goote2
1From the New York Plastic Surgical Group.
Background:
Smoking's impact on tissue perfusion and wound healing is particularly relevant in rhinoplasty, where precise tissue healing is crucial for functional and aesthetic outcomes. Although the nasal region's robust vascular supply mitigates smoking's detrimental effects, concerns remain about postoperative complications. This study investigates whether smoking should be contraindicated for rhinoplasty by comparing infection and revision rates between smokers and nonsmokers.
Methods:
A retrospective review was conducted on 1884 rhinoplasty cases from 2014 to 2022. Patients were categorized as active smokers, former smokers, or nonsmokers. Only patients with at least 12 months of follow-up were included. All procedures were open rhinoplasties conducted under general anesthesia. Primary outcomes analyzed included infection and revision rates. Between-group statistical comparisons were performed.
Results:
A total of 1884 patients consisted of 80 active smokers, 39 former smokers, and 1765 nonsmokers. Average follow-up was 23.8 months. The overall revision rate was 3.3%, with 3.8% in smokers and 3.3% in nonsmokers; 3.8% of smokers required additional antibiotics for cellulitis compared with 1.6% of nonsmokers; all cases resolved without long-term complications. There were no significant differences between smoker and nonsmoker rhinoplasty patients in rates of revision, postoperative infection, or wound complications.
Conclusions:
Active smoking does not appear to be a strict contraindication for rhinoplasty. Smoker and nonsmoker primary and revision rhinoplasty patients exhibited similar revision, postoperative infection, and wound complication rates. This suggests that, with proper perioperative optimization, rhinoplasty can be safely performed in smokers. Although smoking cessation should still be recommended, it may not be mandatory for satisfactory outcomes.
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