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Updated: Jun 13, 2025
Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
Invasive pulmonary aspergillosis often misdiagnosed as lung cancer: A case report
Ruiping Bu1,2, Yanhong Zong3, Jianping Xu2
1Department of Internal Medicine, Graduate School of Hebei Medical University, Shijiazhuang, Hebei, China.
Rationale:
The incidence of epidemiological pulmonary aspergillosis (PA) is increasing worldwide. Diagnosis of PA is challenging because of the nonspecificity of its clinical manifestations and imaging characteristics. PA has a high mortality rate, making early diagnosis and treatment critical.
Patient Concerns:
A 67-year-old female patient was admitted to the hospital with a half-month history of cough, blood-tinged sputum, and a sore throat. The patient had no history of chronic diseases, such as hypertension, coronary heart disease, or diabetes. The patient had a family history of cancer.
Diagnoses:
The patient was diagnosed with invasive pulmonary aspergillosis (IPA).
Interventions:
After the diagnosis of IPA, the patient underwent antifungal treatment with oral voriconazole.
Outcomes:
After treatment, the patient's symptoms improved, and a follow-up chest computed tomography scan showed a reduction in the area of inflammation.
Lessons:
Immunocompetent individuals may develop IPA. The clinical and imaging manifestations of IPA vary, which makes misdiagnosis possible. When necessary, a pathological biopsy can be performed to confirm the diagnosis.
