Related Experiment Video
Updated: Jan 18, 2026
06:37
Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice
Published on: September 13, 2024
1.9K
Association Between Cardiovascular Autonomic Function and Temporomandibular Disorders.
Niklas Kakko1, Auli Suominen2, Atte Somero2
1Research Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland.
Journal of Oral Rehabilitation
|June 10, 2025
Summary
Lowered baroreflex sensitivity, indicating increased sympathetic tone, is associated with temporomandibular disorder (TMD) pain in females. This suggests stress response plays a role in TMD development.
Area of Science:
- Neuroscience
- Cardiovascular Physiology
- Pain Management
Background:
- Elevated stress levels are linked to temporomandibular disorder (TMD) pain.
- Autonomic tone alterations may contribute to TMD pathophysiology.
Purpose of the Study:
- To investigate sex-specific associations between autonomic nervous system (ANS) activity and TMD pain diagnoses.
- Utilizing a population-based cohort for robust analysis.
Main Methods:
- Assessed ANS activity via heart rate variability (HRV) and baroreflex sensitivity (BRS).
- Diagnosed TMD using the modified DC/TMD protocol, focusing on myalgia and arthralgia.
- Employed logistic regression analyses stratified by sex, controlling for confounders like BMI and education.
Main Results:
- Females with TMD myalgia or arthralgia exhibited significantly lower baroreflex sensitivity (BRS) while standing.
- Adjusted odds ratios indicated a significant association between lower BRS and TMD pain diagnoses in females.
Conclusions:
- Reduced baroreflex sensitivity, indicative of heightened sympathetic tone, is associated with TMD pain in females.
- Findings support the link between stress response mechanisms and the development of TMD pain.
Related Concept Videos
01:18Disorders of the Autonomic Nervous System
1.4K
The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
Raynaud's disease, also known as Raynaud's...
1.4K
01:27Psychoneuroimmunology: Cardiovascular Disease
407
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
407
01:23Assessment of the Cardiovascular System I: Subjective Data
759
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
759
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
501
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
501
01:18Neural Regulation of Blood Pressure
6.9K
The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
6.9K