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Updated: Sep 19, 2025

Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection
Published on: August 20, 2007
New Perspectives and Approaches to Transplant Selection Committee
1Von Liebig Transplant Center, Mayo Clinic, Rochester, MN, USA.
None:
The transplant selection process for solid organ recipients relies on committee review and is susceptible to human nature and bias. The current model of selection committees has been under-examined and untested. Few studies exist on transplant selection committees. Barriers to quality decision-making have been studied in other industries. Lessons learned in other industries were explored and how they may be applied to a transplant selection committee. These include appointing an ethical representative or an advocate (pro) and dissenter (against) for discussion, adopting an ideal committee size/composition, and reviewing previous committee decisions (post-mortem). The transplant selection committee can function beyond a singular decision and be an opportunity to identify gaps in patients' treatment plans and available resources. Looking forward, a transplant selection committee that is more consistent, equitable, and protocolized can reduce bias, moral burden, and missed listings for our patients.
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