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Updated: Sep 19, 2025

Metal-free Synthesis of Ynones from Acyl Chlorides and Potassium Alkynyltrifluoroborate Salts
Published on: February 24, 2015
Solvent-Controlled Ring-Opening Halogenation and Halosulfonation of Alkynyl Sulfonium Salts with Alkali Halides
Li Yang1, Qian-Zhi Yang1, Jia Shu2
1Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, 443002 Yichang, China.
Abstract:
A highly efficient and convenient method for KX-promoted ring-opening halogenation and halosulfonation of alkynyl sulfonium salts has been developed. This reaction facilitates the selective synthesis of various halogenated and halosulfonated ring-opening products in good to high yields under different solvent conditions. Importantly, the resulting products can be further transformed into a diverse array of valuable functionalized molecules, highlighting the practicality of this method in organic synthesis.
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