Related Experiment Video
Updated: Jul 4, 2026

07:27
Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
24.8K
Congenital Complete Heart Block Requiring Temporary Pacemaker Placement at Birth: A Case Report
Karthi Murari1, Clint Humpherys2, Nathaniel Lata2
1University of Kansas School of Medicine, Kansas City, KS, USA.
Seminars in Cardiothoracic and Vascular Anesthesia
|June 10, 2025
Summary
Congenital complete heart block (CCHB) in a fetus was diagnosed and managed through multidisciplinary care. This case highlights the importance of early detection and coordinated management for successful outcomes in neonatal cardiovascular care.
Area of Science:
- Cardiology
- Immunology
- Maternal-Fetal Medicine
Background:
- Congenital heart block (CHB) is a rare condition affecting fetal cardiac conduction.
- Neonatal lupus antibodies, particularly SSA antibodies, are a common cause of CHB, leading to AV node destruction.
- Congenital complete heart block (CCHB) is the most frequent manifestation.
Purpose of the Study:
- To report a case of fetal bradycardia diagnosed as third-degree heart block.
- To emphasize the critical role of multidisciplinary coordination in managing fetal and neonatal CCHB.
- To discuss the etiology, diagnosis, and management of fetal cardiac abnormalities and CCHB.
Main Methods:
- Fetal ultrasound and echocardiography for diagnosis of bradycardia and heart block.
- Maternal serological testing for SSA antibodies.
- Multidisciplinary team approach for antepartum, delivery, and neonatal care.
Main Results:
- A 23-year-old mother's fetus was diagnosed with third-degree heart block at 21 weeks gestation.
- Maternal testing revealed positive SSA antibodies.
- Successful management involved coordinated care from pregnancy through neonatal cardiovascular support.
Conclusions:
- Early diagnosis of fetal bradycardia and CCHB is crucial.
- Maternal SSA antibodies are a significant risk factor for CCHB.
- Multidisciplinary planning and preparation are essential for optimizing outcomes in high-risk fetal cardiac interventions and neonatal care.
Related Concept Videos
Pulse rhythm
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Conduction System of the Heart
Autorhythmicity is a term that refers to the heart's inherent ability to generate electrical signals and instigate muscle contractions. This self-regulating conduction system within the heart consists of two key components: the pacemaker cells and specialized conducting cells.
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
Disturbances in Heart Rhythm
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Dysrhythmias IV: Characteristics of Bradyarrhythmias
Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...

