A Case-Control Study Examining the Differences in Vitamin D Levels Between Individuals With Rosacea and Healthy...

Area of Science:

• Dermatology
• Endocrinology
• Nutritional Science

Background:

• Rosacea is a chronic inflammatory skin condition with multifactorial causes.
• The role of vitamin D in rosacea pathogenesis is not fully understood.
• Investigating nutrient levels like vitamin D may offer insights into rosacea management.

Purpose of the Study:

• To compare serum vitamin D levels in patients diagnosed with rosacea versus healthy controls.
• To determine if vitamin D deficiency is associated with rosacea.
• To analyze vitamin D levels in relation to demographic factors and disease severity in rosacea patients.

Main Methods:

• A case-control study involving 62 participants was conducted in Isfahan, Iran.
• Participants were classified into rosacea (case) and healthy (control) groups based on established diagnostic criteria.
• Serum vitamin D levels, age, and gender were recorded for all participants.

Main Results:

• The mean vitamin D level in the rosacea group (29.9 ± 2.95) was numerically higher than in the control group (24.5 ± 2.14).
• This difference in vitamin D levels between the groups did not reach statistical significance (p > 0.05).
• No significant association was found between vitamin D levels and gender or rosacea severity subgroups.

Conclusions:

• Serum vitamin D levels do not significantly differ between individuals with rosacea and healthy individuals.
• The current findings suggest vitamin D levels are unlikely to be a primary factor in rosacea development or severity.
• Further investigation with larger cohorts may be warranted to definitively rule out subtle associations.