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Updated: Mar 22, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Audit and Feedback Supporting New Guideline Implementation in Chronic Kidney Disease
Megan E Lanpher1,2, Brooke Patterson1, Muhammad Ebrahim2
1College of Nursing, University of South Carolina, Columbia.
Background:
Adults with Type 2 diabetes mellitus and chronic kidney disease experience higher risk for progression to end stage kidney disease, which negatively impacts health, increases medical costs, and decreases quality of life.
Objective:
Determine if an audit and feedback intervention in a local nephrology clinic can increase provider adherence to a clinical practice guideline that supports the prescription of sodium glucose cotransporter-2 inhibitors to delay progression of chronic kidney disease.
Design:
A pretest-posttest design was used to determine if an audit and feedback tool delivered to providers at 3-week intervals would increase provider adherence to the guideline recommendation over the course of 3 months. A clinical decision guide was provided to participants at the onset of the intervention with structured interviews accompanying the audit and feedback cycles.
Participants:
English speaking physicians and advanced practice providers were recruited from a local nephrology outpatient clinic in the southeastern United States.
Measurements:
To evaluate the significance of the intervention, a chi-square test was used to evaluate the change in prescribing of SGLT-2 inhibitors compared to the 3 months before the intervention. Logistic regression assisted with examining the relationship between the intervention and proportion of new SGLT-2 inhibitor prescriptions.
Results:
In this setting, statistical analysis indicated that the intervention significantly increased prescription of SGLT-2 inhibitors in adults with Type 2 diabetes and chronic kidney disease.
Conclusion:
The intervention significantly increased provider adherence to the clinical guideline. Additional implementation on a larger scale is warranted to validate findings and further investigate barriers to prescribing that were reported by participating providers.
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