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Updated: Jun 14, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Properties of Measurements of Patient-Reported Outcome Measures Physical Activity Assessment in Chronic Kidney
Thamiê Cristina Stella1, Inaê Silva Santos1, Graziella Alves da Silva1
1Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho, São Paulo, Brazil.
Background And Purpose:
The assessment of physical activity (PA) using Patient-Reported Outcome Measures (PROMs) is routine due to its easy applicability and low cost. In the context of CKD, there are several studies that evaluate PA through PROM, but there is heterogeneity in the choice of tool. Therefore, the objective of this study was to identify, evaluate and synthesize the psychometric properties of PROMs used in the assessment of PA in CKD.
Methods:
A systematic review was carried out according to the PRISMA guidelines in PubMed, SciELO, Medline, Lilacs and EMBASE databases. The assessment of the quality of the studies was evaluated using the COSMIN Checklist and EMPRO tool.
Results:
15,137 studies were found, with 17 included. Eleven PROMs were found, of which 2 were elaborate to the CKD population: Chronic Kidney Disease Physical Activity Questionnaire (CKD-PAQ) and Low Physical Activity Questionnaire (LoPAQ). Criterion validity was the most evaluated psychometric property. Only CKD-PAQ shows satisfactory results in both evaluation tools for the psychometric properties evaluated.
Discussion:
This systematic review found no consensus in the literature for the best PROM for assessing PA in CKD. However, the CKD-PAQ appears to be promising as the only PROM with a favorable evaluation by both COSMIN RoB and EMPRO. There is a lack of studies evaluating PA in the early stages of CKD and its responsiveness, indicating a gap in the research. COSMIN RoB and EMPRO differed from each other, showing that the choice of the evaluation tool must be guided by the evaluator's expertise and objective.
Trial Registration:
Systematic review registered in PROSPERO (CRD42022312143).
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