A plaque recognition algorithm for coronary OCT images by Dense Atrous Convolution and attention mechanism

He Meng1, Ran Zhao2,3, Ying Zhang1

  • 1Chest hospital, Tianjin University, Tianjin, China.

Plos One
|June 10, 2025
PubMed

Insights

This study introduces a new deep learning algorithm for precise automated segmentation of coronary artery plaques in Optical Coherence Tomography (OCT) images, significantly improving accuracy over existing methods.

Area of Science:

  • Medical Imaging
  • Artificial Intelligence in Medicine
  • Cardiovascular Imaging

Background:

  • Manual plaque segmentation in coronary Optical Coherence Tomography (OCT) images is time-consuming and prone to inaccuracies.
  • Existing automated segmentation techniques require further refinement for clinical application.

Purpose of the Study:

  • To develop a novel deep learning algorithm for high-precision segmentation and classification of coronary artery plaques.
  • To provide an efficient and accurate automated decision support tool for physicians.

Main Methods:

  • A novel deep learning algorithm integrating Dense Atrous Convolution (DAC) and an attention mechanism was developed.
  • A dataset of 760 original OCT images was augmented to 8,000 images for training and validation.

Main Results:

  • The proposed algorithm achieved high dice coefficients: 0.913 for calcified, 0.900 for fibrous, and 0.879 for lipid plaques.
  • Performance surpassed five conventional medical image segmentation networks.
  • Demonstrated superior effectiveness in automatic coronary artery plaque segmentation.

Conclusions:

  • The developed deep learning algorithm offers a significant advancement in automated coronary artery plaque segmentation using OCT.
  • The algorithm provides a reliable and superior alternative to manual segmentation and existing automated methods.
  • The enhanced dataset serves as a valuable resource for future research in cardiovascular plaque analysis.