Characteristics Associated With Disseminated Gonococcal Infections vs Uncomplicated Gonorrhea: A California
Kelly A Johnson1,2, Roshani Fernando1, Rosalyn Plotzker1,3
1Division of Communicable Disease Control, Center for Infectious Diseases, California Department of Public Health, Sexually Transmitted Diseases (STD) Control Branch, Richmond, California, USA.
Summary
People not prioritized for routine gonorrhea screening, including heterosexual men, substance users, and older adults, face higher odds of disseminated gonorrhea. This highlights gaps in public health surveillance for sexually transmitted infections.
Area of Science:
- Public Health
- Infectious Diseases
- Epidemiology
Background:
- Gonorrhea (GC) remains a significant public health concern globally.
- Disseminated gonorrhea (GC) represents a more severe manifestation of infection.
- Current screening strategies may not adequately reach all at-risk populations.
Purpose of the Study:
- To identify demographic and behavioral factors associated with an increased risk of disseminated gonorrhea.
- To evaluate disparities in gonorrhea (GC) outcomes based on routine screening prioritization.
Main Methods:
- Retrospective analysis of gonorrhea (GC) case data.
- Comparison of odds of disseminated versus uncomplicated GC.
- Inclusion of factors such as sexual orientation, substance use, and age.
Main Results:
- Individuals not prioritized for routine GC screening exhibited higher odds of disseminated disease.
- Specific risk groups identified include heterosexual men, people using substances, and older individuals.
- Significant odds ratios were observed for these non-prioritized groups.
Conclusions:
- Routine gonorrhea (GC) screening may need to be expanded to include under-prioritized populations.
- Targeted interventions are crucial for preventing severe outcomes of gonorrhea (GC).
- Public health strategies should address social determinants impacting STI risk and outcomes.
Related Concept Videos
Sexually Transmitted Infections
286
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
286
Genome-wide Association Studies-GWAS
13.2K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
13.2K


