Abstract
A 6-year-old boy with a history of neuroblastoma following chemotherapy presented with positive bone marrow minimal residual disease (MRD). 123I-MIBG SPECT/CT did not reveal any avid lesions, given the positive MRD and high clinical suspicion for disease recurrence, a subsequent 68Ga-DOTATATE PET/CT was performed. This modality identified multiple metastatic lesions that were avid for 68Ga-DOTATATE. Histopathological examination confirmed the diagnosis of neuroblastoma metastasis. This case underscores the complementary diagnostic value of 68Ga-DOTATATE PET/CT in patients with negative 123I-MIBG findings, particularly when there are indications of potential relapse.
