Related Experiment Video

Updated: Jun 12, 2025

Establishment and Evaluation of a Porcine Vein Graft Disease Model
08:50

Establishment and Evaluation of a Porcine Vein Graft Disease Model

Published on: July 25, 2022

1.7K

The Impact of COVID-19 on Graft Vasculopathy and Postoperative Thromboembolism in CABG Patients: A Prospective

İlknur Şahin1, Şebnem Batur2, Ahmet Üstündağ3

  • 1Basaksehir Cam Ve Sakura City Hospital, Cardiovascular Surgery Clinic, University of Health Sciences, Istanbul, Turkey.

Cardiovascular Toxicology
|June 10, 2025
PubMed

Insights

Patients with a mild history of COVID-19 can safely undergo Coronary Artery Bypass Grafting (CABG) surgery after a four-week recovery. Early postoperative vascular outcomes, including graft patency and inflammation, showed no significant differences compared to patients without a COVID-19 history.

Area of Science:

  • Cardiovascular Surgery
  • Infectious Diseases
  • Pathology

Background:

  • COVID-19 can cause endothelial dysfunction and coagulation issues, potentially impacting graft patency in Coronary Artery Bypass Grafting (CABG).
  • Assessing the long-term vascular effects of COVID-19 on CABG patients is crucial for surgical planning and patient outcomes.

Purpose of the Study:

  • To investigate the vasculitic effects of a prior COVID-19 infection in patients undergoing CABG surgery.
  • To compare early postoperative vascular outcomes between CABG patients with and without a history of mild COVID-19.

Main Methods:

  • A cohort of 94 patients (34 with prior mild COVID-19, 60 without) scheduled for CABG were included.
  • Patients with COVID-19 history had surgery at least 4 weeks post-recovery.
  • Vascular grafts were pathologically evaluated for vasculitis/inflammation, and thromboembolic events were monitored.

Main Results:

  • No significant differences were observed in vein thrombosis/thrombophlebitis between the groups (p=0.626).
  • Pathological examination revealed no signs of vasculitis or inflammation in grafts from either group.
  • Postoperative mortality and morbidity rates were comparable between patients with and without a history of COVID-19 (p>0.05).

Conclusions:

  • Undergoing CABG surgery at least four weeks after mild COVID-19 recovery appears safe regarding early vascular outcomes.
  • A history of mild COVID-19 does not significantly increase the risk of early graft complications or adverse surgical outcomes.

Keywords:
CABGCOVID-19InflammationVasculitis

More Related Videos

Author Spotlight: Enhancing Coronary Artery Revascularization05:25

Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

649
Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg00:09

Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg

Published on: November 19, 2019

8.6K

Related Concept Videos

Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
4
Coronary Artery Disease V: Surgical Management01:27

Coronary Artery Disease V: Surgical Management

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
3
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
3
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
3
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
48
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
3