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Clinical Application of Microscope-Assisted Minimally Invasive Anterior Lumbar Interbody Fusion
Published on: June 16, 2023
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Intraoperative Venous Injury During Anterior Lumbar Interbody Fusion: Incidence, Risk Factors, and Complications
Henry Avetisian1, Camille Flynn1, Rakhi Banerjee1
1Department of Orthopaedic Surgery, Keck School of Medicine of the University of Southern CA, Los Angeles, CA, USA.
Global Spine Journal
|June 11, 2025
Summary
Intraoperative venous injury occurred in 16.61% of anterior lumbar interbody fusion (ALIF) cases. Risk factors include age, chronic kidney disease, and multi-level ALIF, increasing deep vein thrombosis (DVT) risk.
Area of Science:
- Spine surgery
- Vascular injury
- Epidemiology
Background:
- Anterior lumbar interbody fusion (ALIF) is a common spinal procedure.
- Intraoperative venous injuries are a potential complication during ALIF.
- Understanding risk factors and outcomes is crucial for patient safety.
Purpose of the Study:
- To determine the incidence of intraoperative venous injury during ALIF.
- To identify independent risk factors associated with venous lacerations.
- To evaluate the complications linked to these injuries, including deep vein thrombosis (DVT).
Main Methods:
- Retrospective cohort study of patients undergoing ALIF.
- Exclusion of patients under 18 or with trauma, infection, or malignancy.
- Statistical analyses including logistic regression to identify risk factors and complications.
Main Results:
- Venous laceration occurred in 16.61% of 554 patients.
- Independent risk factors: older age, chronic kidney disease, L4-5 and two-level ALIF.
- Protective factor: L5-S1 ALIF.
- Injuries associated with longer operative time, increased blood loss, and higher risk of DVT, transfusion, and wound complications.
Conclusions:
- Venous laceration is a significant complication in ALIF, affecting 16.61% of patients.
- Age, CKD, and specific ALIF levels/multiplicity are key risk factors.
- Venous injuries increase operative time, blood loss, and DVT risk, necessitating targeted prevention strategies and VTE prophylaxis.
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