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Revisiting Late-Onset Bipolar Disorder Associated With Pituitary Adenoma: A Cross-Sectional, Multidisciplinary,
Yagmur Sever Fidan1, Ikbal Humay Arman2, Sumeyye Yasemin Calli1
1Erenkoy Mental and Nervous Diseases Training and Research Hospital, Istanbul, Turkiye.
Brain and Behavior
|June 11, 2025
Summary
Managing late-onset bipolar disorder (BD) in elderly patients requires collaboration. Specialists have unique strengths and weaknesses, necessitating integrated care for better patient outcomes.
Area of Science:
- Geriatric Psychiatry
- Neurology
- Family Medicine
Background:
- Late-onset bipolar disorder (BD) presents unique diagnostic and management challenges in elderly populations.
- Effective care necessitates understanding the distinct approaches and limitations of various medical specialties.
Purpose of the Study:
- To explore and compare the diagnostic, treatment, and follow-up strategies of neurologists, psychiatrists, and family physicians for late-onset BD in elderly patients.
- To identify barriers and facilitators of interdisciplinary collaboration in managing this patient group.
Main Methods:
- A cross-sectional survey was conducted among 300 specialists (100 neurologists, 100 psychiatrists, 100 family physicians).
- The survey assessed diagnostic accuracy, treatment preferences, follow-up adherence, and interdisciplinary collaboration barriers.
- Comparative analysis using pairwise z-tests with Bonferroni correction evaluated differences across specialties.
Main Results:
- Neurologists excelled in imaging (91%) but lagged in holistic management (2%). Psychiatrists were adept at diagnosing organic causes (92%) but struggled with non-priority tests (44%) and long-term follow-up (14%).
- Family physicians demonstrated strong pharmacological management (96%) and follow-up adherence (89%) but faced stigma and referral timing issues.
- Common interdisciplinary challenges included diagnostic communication, treatment coordination, and follow-up collaboration.
Conclusions:
- A multidisciplinary approach is crucial for late-onset BD, addressing specialty-specific deficits and enhancing collaboration.
- Recommendations include improved training, integrated care models, and shared guidelines to optimize outcomes for elderly mood disorder patients.
- Future research should focus on standardized protocols and evaluating the impact of interdisciplinary interventions.
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