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Generalized Lymphadenopathy in an 8-Month-Old Infant: Visual Diagnosis
Sobia Nawaz1, Huma Naser1, Ratna Basak1
1Pediatrics, University Hospital at Downstate and Kings County Hospital Center, New York, NY, USA.
Journal of Child Neurology
|June 11, 2025
Summary
Tuberculosis (TB) is rising in the US, particularly in infants. Early diagnosis and treatment of infant TB, like military TB, are crucial to prevent transmission and severe illness.
Area of Science:
- Pediatrics
- Infectious Diseases
- Radiology
Background:
- Tuberculosis (TB) cases are increasing in the US, with infants and children disproportionately affected.
- Infants' immature immune systems make them vulnerable to disseminated TB infections.
- Timely diagnosis and treatment are essential to prevent TB transmission and reduce morbidity.
Purpose of the Study:
- To highlight the diagnostic challenges of military tuberculosis in an infant.
- To emphasize the importance of considering TB in the differential diagnosis of infant illnesses.
- To review the role of radiological imaging in diagnosing disseminated TB.
Main Methods:
- Case presentation of an 8-month-old infant with lymphadenopathy and increasing head circumference.
- Diagnostic evaluation including radiological imaging (X-ray, CT-scan, MRI).
- Review of literature on infant TB diagnosis and management.
Main Results:
- The infant was diagnosed with military tuberculosis.
- Radiological findings, though not explicitly detailed, were crucial in diagnosis.
- The case underscores the need for a broad differential diagnosis in infants presenting with non-specific symptoms.
Conclusions:
- Military TB in infants requires prompt recognition and management.
- Radiological evaluations are vital for diagnosing disseminated TB when symptoms are ambiguous.
- This case contributes to understanding the varied presentations of TB in infants.

