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Related Concept Videos

Intracellular Movement of Viruses and Bacteria01:10

Intracellular Movement of Viruses and Bacteria

Intracellular bacteria and viruses often comprise a group of highly infectious pathogens that can cause several diseases. Bacterial pathogens include those belonging to the genus Rickettsia responsible for conditions such as rocky mountain spotted fever and the Mediterranean spotted fever; Chlamydia, a genus responsible for a sexually transmitted disease; Coxiella burnetii, an agent responsible for Q fever. Viral pathogens include vaccinia—a poxvirus, and herpes simplex virus—a virus that...
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Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
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Biosynthesis in Bacteria

Biosynthesis in bacteria is a fundamental anabolic process that generates essential macromolecules, including proteins, nucleic acids, lipids, and polysaccharides. These macromolecules are critical for cellular growth, replication, and function. The process is tightly regulated and energetically linked to catabolic pathways to ensure optimal resource utilization.Biosynthetic pathways begin with precursor metabolites such as pyruvate, acetyl-CoA, and glucose-6-phosphate derived from glycolysis,...
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Updated: Jun 20, 2026

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes
14:05

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes

Published on: September 19, 2013

Obligate intracellular bacterial pathogens as major players in the metabolic integration of organelles

Steven Ball, Denis Baurain, Marie Leleu

    Comptes Rendus Biologies
    |June 11, 2025
    PubMed
    Summary
    This summary is machine-generated.

    Endosymbiotic organelles like mitochondria and plastids likely arose from intracellular pathogens. These "helper genomes" provided essential gene products, facilitating metabolic integration and the evolution of eukaryotes.

    Keywords:
    ChlamydiaEndosymbiosisMitochondriaMénage à trois hypothesisPlastidsRickettsiales

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    Using a Bacterial Pathogen to Probe for Cellular and Organismic-level Host Responses
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    Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes
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    Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes

    Published on: September 19, 2013

    Using a Bacterial Pathogen to Probe for Cellular and Organismic-level Host Responses
    08:38

    Using a Bacterial Pathogen to Probe for Cellular and Organismic-level Host Responses

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    Investigation of Microbial Cooperation via Imaging Mass Spectrometry Analysis of Bacterial Colonies Grown on Agar and in Tissue During Infection
    09:49

    Investigation of Microbial Cooperation via Imaging Mass Spectrometry Analysis of Bacterial Colonies Grown on Agar and in Tissue During Infection

    Published on: November 18, 2022

    Area of Science:

    • Cell Biology
    • Evolutionary Biology
    • Microbiology

    Background:

    • Endosymbionts are widespread, offering models for organelle origin.
    • Mitochondria and plastids are unique organelles derived from distinct endosymbiotic events.
    • The origin of these organelles is crucial for understanding eukaryotic evolution.

    Purpose of the Study:

    • To compare extant endosymbionts with mitochondria and plastids.
    • To explore the role of intracellular pathogens in organelle establishment.
    • To investigate the preadaptation requirements for endosymbiont metabolic integration.

    Main Methods:

    • Review of current literature on endosymbiosis and organelle evolution.
    • Analysis of similarities and differences between endosymbionts and organelles.
    • Focus on recent findings regarding intracellular pathogens.

    Main Results:

    • Intracellular pathogens may have played a significant role in forming mitochondria and plastids.
    • Metabolic integration required high preadaptation levels not common in extant endosymbionts.
    • Helper genomes or direct selection from intracellular bacteria facilitated organelle origins.

    Conclusions:

    • Endosymbiotic organelle evolution likely involved specialized bacterial partners.
    • Intracellular pathogens provided a unique pathway for acquiring essential functions.
    • This perspective refines our understanding of the early evolution of eukaryotes.